Epinephrine (also referred to as Adrenaline; see Terminology) is a hormone A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another. All multicellular organisms produce hormones; plant hormones are also called and neurotransmitter Neurotransmitters are endogenous chemicals which relay, amplify, and modulate signals between a neuron and another cell. Neurotransmitters are packaged into synaptic vesicles that cluster beneath the membrane on the presynaptic side of a synapse, and are released into the synaptic cleft, where they bind to receptors in the membrane on the.[1] When produced in the body it increases heart rate, contracts blood vessels and dilates air passages and participates in the "fight or flight" response The "fight-or-flight response", also called the "fight-or-flight-or-freeze response", the "fright, fight or flight response", "hyperarousal" or the "acute stress response", was first described by Walter Cannon in 1929 of the sympathetic nervous system The Sympathetic Nervous System is a branch of the autonomic nervous system along with the enteric nervous system and parasympathetic nervous system. It is always active at a basal level (called sympathetic tone) and becomes more active during times of stress. Its actions during the stress response comprise the fight-or-flight response.[2] It is a catecholamine Catecholamines are sympathomimetic "fight-or-flight" hormones that are released by the adrenal glands in response to stress. They are part of the sympathetic nervous system, a sympathomimetic Sympathomimetic drugs are substances that mimic the effects of the sympathetic nervous system, such as catecholamines, epinephrine , norepinephrine (noradrenaline), dopamine, etc. Such drugs are used to treat cardiac arrest, low blood pressure, or even delay premature labor, among other things monoamine Monoamine neurotransmitters are neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by a two-carbon chain . All monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes produced only by the adrenal glands In mammals, the adrenal glands are the star-shaped endocrine glands that sit on top of the kidneys. They are chiefly responsible for releasing hormones in conjunction with stress through the synthesis of corticosteroids and catecholamines, including cortisol and adrenaline (epinephrine), respectively from the amino acids Amino acids are molecules containing an amine group, a carboxylic acid group and a side chain that varies between different amino acids. These molecules are particularly important in biochemistry, where this term refers to alpha-amino acids with the general formula H2NCHRCOOH, where R is an organic substituent. In the alpha amino acids, the amino phenylalanine Phenylalanine is an α-amino acid with the formula HO2CCH(NH2)CH2C6H5. This essential amino acid is classified as nonpolar because of the hydrophobic nature of the benzyl side chain. The codons for L-phenylalanine are UUU and UUC. L-Phenylalanine (LPA) is an electrically-neutral amino acid, one of the twenty common amino acids used to and tyrosine Tyrosine or 4-hydroxyphenylalanine, is one of the 20 amino acids that are used by cells to synthesize proteins. It is a non-essential amino acid with a polar side group. The word "tyrosine" is from the Greek tyros, meaning cheese, as it was first discovered in 1846 by German chemist Justus von Liebig in the protein casein from cheese.
The term Adrenaline is derived from the Latin Latin is an Italic language originally spoken in Latium and Ancient Rome. With the Roman conquest, Latin was spread to countries around the Mediterranean, including a large part of Europe. Romance languages, such as Catalan, French, Italian, Portuguese, Romanian, and Spanish, are descended from Latin, while many others, especially European roots ad- and renes, and literally means on the kidney The kidneys are paired organs, which have the production of urine as their primary function. Kidneys are seen in many types of animals, including vertebrates and some invertebrates. They are an essential part of the urinary system, but have several secondary functions concerned with homeostatic functions. These include the regulation of, in reference to the gland's anatomic location. The Greek Greek , an independent branch of the Indo-European family of languages, is the language of the Greeks. Native to the southern Balkans, it has the longest documented history of any Indo-European language, spanning 34 centuries of written records. In its ancient form, it is the language of classical ancient Greek literature and the New Testament of roots epi- and nephros have similar meanings, and give rise to epinephrine. The term epinephrine is often shortened to epi in medical jargon.[3]
Japanese chemist Jokichi Takamine Jokichi Takamine was a Japanese chemist and samurai and his assistant Keizo Uenaka independently discovered Adrenaline in 1900.[4][5] In 1901 Takamine successfully isolated and purified the hormone from the adrenal glands of sheep and oxen.[6] Adrenaline was first synthesized by Friedrich Stolz Friedrich Stolz was a German chemist and, in 1904, the first person to artificially synthesize epinephrine (adrenaline) and Henry Drysdale Dakin He was born in London as the youngest of 8 children to a family of steel merchants from Leeds. As a school boy he did water analysis with the Leeds City Analyst. He studied chemistry at the University of Leeds with Julius B. Cohen and after he worked with Albrecht Kossel on arginase at the University of Heidelberg he joint Columbia University in 19, independently, in 1904.[5]
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Turkey Valley (10-2) got a jolt of early adrenaline when Brad Winter received the opening kickoff and hot-footed it 92 yards to paydirt. South Winn (11-1), ...
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